Publications

2026

Liver-X-receptor Agonism Enhances T Cell Priming and Activation to Promote Anti-Tumor Immunity

B. N. Ostendorf, J. G. Goldstein, S. Liu, F. C. Gonsalves, J. Bilanovic, M. Yuan, J. Kim, C. Rouya, M. Tavazoie, S. F. Tavazoie

Journal of Experimental Medicine, 2026, 223(4):e20252290

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Co-corresponding authorship

PROTECTOR / FIRE‑10: Study Protocol for a Prospective, Randomized, Open-Label, Multicenter Phase III Trial to Investigate the Efficacy of Preoperative Systemic Therapy in Advanced Colon Cancer

R. Siegel, L. Dittrich, J. Plewe, T. Denecke, J. Leonhardi, A. Tannapfel, A. {Reinacher-Schick}, N. Raschzok, I. M. Sauer, J. Lauscher, S. Lorenzen, T. Götze, I. Jelas, A. Stahler, A. Kurreck, A. Ballhausen, B. N. Ostendorf, O. Haase, J. Pratschke, S. Stintzing, D. P. Modest

BMC cancer, 2026, 26(1):454

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A MERTK-Targeting Antibody–Drug Conjugate Selectively Depletes M2 Tumor-Associated Macrophages and MERTK-Expressing Cancer Cells

S. Takeda, S. Sridhar, D. Schefer, C. {Andreu-Agullo}, P. C. Lo, M. Lee, R. Busby, D. M. Darst, A. Assmus, S. Anaganti, N. Halberg, B. N. Ostendorf, I. C. Lorenz, S. F. Tavazoie, M. F. Tavazoie, I. Kurth

Cancer Research, 2026, 86(8):2024–2041

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2025

Common Hereditary Variants of the APOE Gene and Posttransplant Outcome in Acute Myeloid Leukemia

J. Ronnacker, M. Grau, M. Klasmeier, C. Klesse, H. Baldauf, S. Abert, A. F. Berdel, F. T. Füsser, S. Sandmann, J. Albring, C. Reicherts, S. Call, J. Marx, M. Floeth, E. Eßeling, L. Kolloch, P. Berning, A. Scheller, K. Wethmar, H. Schmidt, B. Schlüter, W. E. Berdel, B. N. Ostendorf, S. F. Tavazoie, J. Mikesch, G. Lenz, K. Fleischhauer, J. Schetelig, M. Stelljes, C. Schliemann

Blood, 2025, 145(17):1943–1956

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BEscreen: A Versatile Toolkit to Design Base Editing Libraries

P. G. Schneider, S. Liu, L. Bullinger, B. N. Ostendorf

Nucleic Acids Research, 2025, 53(W1):W68-W72

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2024

Recapitulating the Tumor Microenvironment in a Dish, One Cell Type at a Time

B. N. Ostendorf

Cell Reports Methods, 2024, 4(6)

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Neuronal Substance P Drives Metastasis through an Extracellular RNA–TLR7 Axis

V. Padmanaban, I. Keller, E. S. Seltzer, B. N. Ostendorf, Z. Kerner, S. F. Tavazoie

Nature, 2024, 633(8028):207–215

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2023

Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis

N. Adaku, B. N. Ostendorf, W. Mei, S. F. Tavazoie

Cancer Research, 2023, 83(18):3013–3025

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2022

Functional Genetic Screen Identifies ITPR3/Calcium/RELB Axis as a Driver of Colorectal Cancer Metastatic Liver Colonization

R. H. Moy, A. Nguyen, J. M. Loo, N. Yamaguchi, C. M. Kajba, B. Santhanam, B. N. Ostendorf, Y. G. Wu, S. Tavazoie, S. F. Tavazoie

Developmental Cell, 2022, 57(9):1146-1159.e7

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Common Human Genetic Variants of APOE Impact Murine COVID-19 Mortality

B. N. Ostendorf, M. A. Patel, J. Bilanovic, H. Hoffmann, S. E. Carrasco, C. M. Rice, S. F. Tavazoie

Nature, 2022, 611(7935):346–351

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Co-corresponding authorship

2021

Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells

X. G. Zhu, A. Chudnovskiy, L. Baudrier, B. Prizer, Y. Liu, B. N. Ostendorf, N. Yamaguchi, A. Arab, B. Tavora, R. Timson, S. Heissel, E. {de Stanchina}, H. Molina, G. D. Victora, H. Goodarzi, K. Birsoy

Cell Metabolism, 2021, 33(1):211-221.e6

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2020

Common Germline Variants of the Human APOE Gene Modulate Melanoma Progression and Survival

B. N. Ostendorf, J. Bilanovic, N. Adaku, K. N. Tafreshian, B. Tavora, R. D. Vaughan, S. F. Tavazoie

Nature Medicine, 2020, 26(7):1048–1053

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Autophagy Suppresses Breast Cancer Metastasis

B. N. Ostendorf, S. F. Tavazoie

Developmental Cell, 2020, 52(5):542–544

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Tumoural Activation of TLR3–SLIT2 Axis in Endothelium Drives Metastasis

B. Tavora, T. Mederer, K. J. Wessel, S. Ruffing, M. Sadjadi, M. Missmahl, B. N. Ostendorf, X. Liu, J. Kim, O. Olsen, A. L. Welm, H. Goodarzi, S. F. Tavazoie

Nature, 2020, 586(7828):299–304

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2018

Phenotypic Characterization of Aberrant Stem and Progenitor Cell Populations in Myelodysplastic Syndromes.

B. N. Ostendorf, E. Flenner, A. Flörcken, J. Westermann

PLoS One, 2018, 13(5):e0197823

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LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer.

M. F. Tavazoie, I. Pollack, R. Tanqueco, B. N. Ostendorf, B. S. Reis, F. C. Gonsalves, I. Kurth, C. {Andreu-Agullo}, M. L. Derbyshire, J. Posada, S. Takeda, K. N. Tafreshian, E. Rowinsky, M. Szarek, R. J. Waltzman, E. A. Mcmillan, C. Zhao, M. Mita, A. Mita, B. Chmielowski, M. A. Postow, A. Ribas, D. Mucida, S. F. Tavazoie

Cell, 2018, 172(4):825-840.e18

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2016

[Flow-cytometric immunophenotyping in clinical diagnostics]

B. N. Ostendorf, L. Hansmann, W. Ludwig, B. Dörken, R. Ratei, J. Westermann

Dtsch med Wochenschr, 2016, 141(21):1569–1574

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2015

Myeloid-Derived Suppressor Cells in Human Peripheral Blood: Optimized Quantification in Healthy Donors and Patients with Metastatic Renal Cell Carcinoma

A. Flörcken, A. Takvorian, A. Singh, A. Gerhardt, B. N. Ostendorf, B. Dörken, A. Pezzutto, J. Westermann

Immunology Letters, 2015, 168(2):260–267

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Severe Radiotoxicity in an Allogeneic Transplant Recipient with a Heterozygous ATM Mutation

B. N. Ostendorf, T. H. Terwey, P. G. Hemmati, D. Böhmer, U. Pleyer, R. Arnold

European Journal of Haematology, 2015, 95(1):90–92

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BCR-ABL Mutation-Guided Therapy for CML Blast Crisis: A Case Report

B. N. Ostendorf, H. Nogai, C. D. Baldus, T. Burmeister, R. Arnold

Biomarker Insights, 2015, 10(s3):BMI.S22279

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Association between Low Uric Acid Levels and Acute Graft-versus-Host Disease.

B. N. Ostendorf, O. Blau, L. Uharek, I. W. Blau, O. Penack

Annals of Hematology, 2015, 94(1):139–144

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2014

Synchronous Tuberculosis, Epstein-Barr Virus-Associated Lymphoproliferative Disorder and Cytomegalovirus Infection in an Allogeneic Transplant Recipient: A Case Report

B. N. Ostendorf, C. F. Jehn, L. G. Vuong, H. Nogai, P. G. Hemmati, B. Gebauer, O. Penack, I. W. Blau, I. Anagnostopoulos, R. Arnold

SpringerPlus, 2014, 3(1):278

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Nilotinib

B. N. Ostendorf, P. {le Coutre}, T. D. Kim, A. {Quintás-Cardama}

Small Molecules in Oncology, 2014

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2013

A Novel Domain Regulating Degradation of the Glomerular Slit Diaphragm Protein Podocin in Cell Culture Systems.

M. Gödel^*, B. N. Ostendorf^*, J. Baumer, K. Weber, T. B. Huber

PloS one, 2013, 8(2):e57078

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^* Shared first authorship

2011

Human Staphylococcus Intermedius Infection in a Patient With Postradiation Changes

B. N. Ostendorf, R. L. Oehler, J. N. Greene

Infectious Diseases in Clinical Practice, 2011, 19(6):426–427

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